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Image Reconstruction in the Positron Emission Tomography

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M. Zioga, A. Nikopoulou, M. Alexandridi, D. Maintas, M. Mikeli, A.-N. Rapsomanikis, E. Stiliaris
M. Zioga, A. Nikopoulou, M. Alexandridi, D. Maintas, M. Mikeli, A.-N. Rapsomanikis, E. Stiliaris

Abstract


Positron Emission Tomography (PET) has become a valuable tool with a broad spectrum of clinical applications in nuclear imaging. PET scanners can collect in vivo information from positron radiotracer distributions, which is further recon- structed to a tomographic image with the help of well established analytical or iterative algorithms. In this current work, an innovative PET image reconstruction method from raw data based on a simple mathematical model is presented. The developed technique utilizes the accumulated density distribution in a predefined voxelized volume of interest. This distribution is calculated by intersecting and weighting the two-gamma annihilation line with the specified voxels. In order to test the efficiency of the new algorithm, GEANT4/GATE simulation studies were performed. In these studies, a cylindrical PET scanner was modeled and the photon interaction points are validated on an accurate physical basis. An appropriate cylin- drical phantom with different positron radiotracers was used and the reconstructed results were compared to the original phantom.


Keywords


PET; Image Reconstruction Algorithms; Monte-Carlo Simulation; GEANT4/GATE

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References


Charles L. Epstein: Introduction to the Mathematics of Medical Imaging, Society for Industrial & Applied Mathematics, 2nd edition (2007) ISBN: 978- 0898716429.

Thorsten M. Buzug: Computed Tomography, Springer Verlag (2008) ISBN: 978-3540394075.

D.L. Bailey, D.W. Townsend, P.E. Valk, M.M. Maisey (Editors): Positron Emission Tomography, Springer Verlag (2003) ISBN: 978-1852337988.

S. Vandenberghe et al.: Iterative Reconstruction Algorithms in Nuclear Medicine, Computerized Medical Imaging and Graphics 25 (2001) 105–111.

S. Jan et al.: GATE: A Simulation Toolkit for PET and SPECT, Phys. Med. Biol. 49 (2004) 4543-4561 and OpenGATE Collaboration http://www.opengatecollaboration.org

R. Lecomte et al.: Design and Engineering Aspects of a High Resolution Positron Tomograph for Small Animal Imaging IEEE Transactions on Nuclear Science 41 (1994) 1446-1552.




DOI: http://dx.doi.org/10.12681/hnps.2490

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Copyright (c) 2019 M. Zioga, A. Nikopoulou, M. Alexandridi, D. Maintas, M. Mikeli, A.-N. Rapsomanikis, E. Stiliaris

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